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And so, another working week will soon draw to a close. This is, as you know, our treasured signal to daydream about weekend plans. Our agenda is reasonably modest. We plan to hang with our shortest person, catch up on some reading, and promenade extensively with the official mascot. And what about you? Spring is springing, so this is a fine time to enjoy the great outdoors. You could also tidy up around your castle. Or you may want to plan for the future by stocking up on sundry goods before prices rise still further. Well, whatever you do, have a grand time. But be safe. Enjoy, and see you soon. …

Researchers testing repurposed drugs against Covid-19 found that ivermectin did not reduce hospital admissions, in the largest trial yet of the effect of the antiparasitic on the disease driving the pandemic, The Wall Street Journal reports. Most evidence has shown the drug to be ineffective against Covid-19 or has relied on data of poor quality. Public-health authorities and researchers have said the drug has not shown any benefit in treating the disease. Regulators warned taking large doses is dangerous. The latest trial, of nearly 1,400 Covid-19 patients at risk of severe disease, is the largest to show those given ivermectin as a treatment did not fare better than those who were given a placebo.

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